Tenvir 300mg Tablet contains Tenofovir Disoproxil Fumarate, an antiviral medication used to treat HIV-1 infection and chronic hepatitis B infection. Tenofovir functions as a nucleotide reverse transcriptase inhibitor (NRTI) by preventing the virus from using an enzyme that it needs to replicate.
Brand Name: Tenvir
Composition: Tenofovir Disoproxil Fumarate
Mechanism of Action:
A prodrug of tenofovir, tenofovir disoproxil fumarate is transformed by the body into its active form, tenofovir diphosphate. Reverse transcriptase, an enzyme essential to HIV and HBV replication and dissemination, is inhibited by this active form. Tenvir helps reduce the viral load in the blood by stopping the virus from reproducing.
Uses:
HIV Infection
Chronic Hepatitis B Infection
Dosage and Administration:
One tablet taken once a day, with or without food, is the usual dosage.
Side Effects:
- Fatigue
- Headache
- Nausea
- Vomiting
- Fever
- Cough
- Insomnia
- Liver Function Abnormalities
- Allergic Reactions
Safety Advise:
Kidney 
Monitor kidney function regularly, as Tenvir can cause nephrotoxicity. Kindly speak with your healthcare provider.
Liver 
Monitor liver function regularly, as Tenvir can cause liver impairement. Kindly speak with your healthcare provider.
Pregnancy 
Tenvir should be used during pregnancy only if clearly needed, Kindly speak with your healthcare provider.
Breast Feeding 
Using Tenvir while nursing is most likely dangerous. Kindly speak with your healthcare provider.
Alcohol 
Tenvir should not be taken with alcohol. Kindly speak with your healthcare provider.
Storage:
Store Tenvir Tablet at a temperature between 15°C and 30°C (59°F to 86°F). Keep the tablets in the original packaging to protect them from light and moisture. Keep out of reach of children.
How to use this Medication?
Drink a glass of water along with this prescription. Take it daily at the same time as specified on the prescription label. Consume it with food. Take each dose exactly as directed on the prescription label for the best potential outcome from your therapy. Don't miss any dosages. The virus may become resistant to this and other medications if doses are skipped. Unless instructed otherwise by your care team, continue taking this therapy.
Discuss the usage of this drug in children with your care team. For certain illnesses, it can be administered to youngsters as young as 12, although there are safety precautions to take.
References:
1. Gallant JE, Deresinski S. Tenofovir disoproxil fumarate. Clinical Infectious Diseases. 2003 Oct 1;37(7):944-50.
2. Kearney BP, Flaherty JF, Shah J. Tenofovir disoproxil fumarate: clinical pharmacology and pharmacokinetics. Clinical pharmacokinetics. 2004 Aug;43:595-612.
3. Lyseng-Williamson KA, Reynolds NA, Plosker GL. Tenofovir disoproxil fumarate: a review of its use in the management of HIV infection. Drugs. 2005 Feb;65:413-32.
4. Fung HB, Stone EA, Piacenti FJ. Tenofovir disoproxil fumarate: a nucleotide reverse transcriptase inhibitor for the treatment of HIV infection. Clinical therapeutics. 2002 Oct 1;24(10):1515-48.
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Marketer details
Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Country of origin: India