Shingrix Vaccine contains Recombinant Herpes Zoster Vaccine. is a two-dose vaccine series (0.5 mL per dose) administered via intramuscular injection in the upper arm. Completing the two-dose sequence is necessary for the prevention of shingles.

Brand Name: Shingrix

Composition: Recombinant Herpes Zoster Vaccine

Mechanism of Action:

The primary target of immunization against the varicella-zoster virus (VZV) is the gE protein. The AS01_B adjuvant improves long-term protection by inducing a robust CD4+ T-cell and antibody response. Shingrix is non-live and recombinant, which makes it safer for immunocompromised people than live vaccinations like Zostavax.

Uses:

Prevention of Herpes Zoster

Dosage and Administration:

It is a two-dose vaccination series that is injected into the upper arm muscle.

Side Effects:

·       Pain, redness, and swelling at the injection site

·       Muscle pain

·       Hives

·       Swelling of the face

·       Tiredness

·       Headache

·       Shivering

·       Fast Heartbeat

·       Fever

·       Upset stomach

Safety Advise:

Lungs  

The safety of Shingrix Vaccine for individuals with lung issues is uncertain. Kindly speak with your healthcare provider.

Liver  

The safety of Shingrix Vaccine for individuals with liver issues is uncertain. Kindly speak with your healthcare provider.

Kidney  

The safety of Shingrix Vaccine for individuals with Kidney issues is uncertain. Kindly speak with your healthcare provider.

Pregnancy  

Shingrix Vaccine should be used during pregnancy only if clearly needed, Kindly speak with your healthcare provider.

Breast Feeding  

Using Shingrix Vaccine while nursing is most likely dangerous. Kindly speak with your healthcare provider. 

Storage:

Keep between 2°C and 8°C (do not freeze).

References:

1.      James SF, Chahine EB, Sucher AJ, Hanna C. Shingrix: the new adjuvanted recombinant herpes zoster vaccine. Annals of Pharmacotherapy. 2018 Jul;52(7):673-80.

2.      Syed YY. Recombinant zoster vaccine (Shingrix®): a review in herpes zoster. Drugs & aging. 2018 Dec;35:1031-40.

3.      Maltz F, Fidler B. Shingrix: a new herpes zoster vaccine. Pharmacy and Therapeutics. 2019 Jul;44(7):406.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: Glaxo SmithKline Pharmaceuticals Ltd

Address: Dr. Annie Besant Road, Mumbai - 400 030

Country of origin: Belgium