Menactra Vaccine is a Meningococcal Conjugate Vaccine (MCV4) that provides protection against invasive meningococcal disease induced by Neisseria meningitidis serogroups A, C, Y, and W-135. Meningococcal polysaccharides and diphtheria toxoid protein are joined in this conjugate vaccine, which greatly enhances immunity, particularly in young infants.

Brand Name: Menactra

Composition: Meningococcal Vaccine (Group A, C, Y & W-135), Diphtheria Toxoid

Mechanism of Action:

Introduces inactivated meningococcal antigens conjugated with diphtheria toxoid, which boosts immune response. encourages the production of defensive antibodies by the body. offers protection against the four primary serogroups of meningococci.

Uses:

·       Prevention of meningococcal disease

·       Prevention of septicemia

Dosage and Administration:

·       9–23 months: 2 doses minimum at least 3 months apart.

·       One 0.5 ml intramuscular injection (ideally deltoid) for individuals aged 2 to 55.

·       Depending on their age and level of exposure, high-risk individuals could require booster doses.

Side Effects:

·       Fever

·       Headache

·       Pain, redness, or swelling at injection site

·       Irritability

·       Drowsiness (in children)

·       Fatigue

·       Malaise

·       Severe allergic reaction

Safety Advise:

Lungs  

The safety of Menactra Vaccine for individuals with lung issues is uncertain. Kindly speak with your healthcare provider.

Liver  

The safety of Menactra Vaccine for individuals with liver issues is uncertain. Kindly speak with your healthcare provider.

Kidney  

The safety of Menactra Vaccine for individuals with Kidney issues is uncertain. Kindly speak with your healthcare provider.

Pregnancy  

Menactra Vaccine should be used during pregnancy only if clearly needed, Kindly speak with your healthcare provider.

Breast Feeding  

Using Menactra Vaccine while nursing is most likely dangerous. Kindly speak with your healthcare provider. 

Storage:

Refrigerate between 2°C and 8°C. Avoid freezing. Protect from light.

How to use this Medication?

Adults and children two years of age and older typically receive Menactra just once. If you have a high risk of meningococcal infection and it has been at least four years since your last vaccination, you could require a booster dose. Younger kids will require two doses.

You can have a different booster schedule. Observe the advice given by your physician or the health department in your area.

You might not be completely protected against illness if you don't take all of the prescribed dosages of Menactra.

Meningococcal vaccines come in various forms. Make sure you are getting a booster shot for meningococcal serogroups A, C, W, or Y rather than serogroup B.

Reference:

1.     Vial M. Menactra (Group. The APRN and PA's Complete Guide to Prescribing Drug Therapy 2024. 2024 Mar 19:389.

2.   Kim HS, Engel S, Neveu D, Thollot Y, Oster P, Yang K. Post-marketing surveillance observational study of quadrivalent meningococcal diphtheria toxoid conjugate vaccine (MenACWY-DT, MCV4/Menactra®) in the Republic of Korea, 2014–2019. Infectious Diseases and Therapy. 2021 Mar;10(1):399-409.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details:

Name: Sanofi India Ltd

Address: Sanofi House, CTS No.117-B, L&T Business Park, Saki Vihar Road, Powai, Mumbai 400072

Country of origin: United states