Lenvat 4mg Capsule contains Lenvatinib, a drug used to treat several cancers, such as thyroid, renal, and hepatocellular carcinomas, is present in the capsule. It functions by blocking particular proteins involved in the creation of blood vessels in tumors and the growth of cancer cells.

Brand Name: Lenvat

Composition: Lenvatinib

Mechanism of Action:

Tyrosine kinase inhibitors (TKIs) include lentinanib. It inhibits several tyrosine kinase receptors, which are proteins involved in the development of blood vessels that supply tumors as well as the growth of malignancies. Lenvatinib limits the blood supply to cancer cells and slows down their development and spread by blocking these receptors.

Uses:

• Thyroid Cancer
• Kidney Cancer
• Liver Cancer
• Endometrial Cancer

Dosage and Administration:

The patient's general health as well as the type of cancer will determine the dosage. Usually, it is taken once a day, either with or without meals.

Side Effects:

• High Blood Pressure
• Diarrhea
• Nausea
• Loss of Appetite
• Fatigue and Weakness
• Weight Loss
• Mouth Sores
• Stomach Pain
• Hoarseness
• Severe Hypertension
• Dark urine
• Irregular heartbeat
• Shortness of breath
• Thyroid Dysfunction
• Proteinuria

Safety Advise:

Liver  

Lenvatinib may affect liver, so periodic blood tests are required. Kindly speak with your healthcare provider.

Kidney  

Lenvatinib may affect kidney function, so periodic blood tests are required. Kindly speak with your healthcare provider.

Pregnancy  

Not recommended for use during pregnancy due to the risk of harm to the unborn baby. Kindly speak with your healthcare provider.

Breastfeeding  

Breastfeeding should be avoided during treatment. Kindly speak with your healthcare provider.

Alcohol  

It is not known whether it is safe to consume alcohol with Lenvat 10 Capsule. Kindly speak with your healthcare provider.

Storage:

Store at room temperature (20°C to 25°C) in a dry place, away from moisture and light. Keep out of reach of children.

How to use this Medication?

When taking this medication, drink a glass of water. Observe the guidelines provided on the prescription label. Completely swallow the capsules. Never chew, cut, or shatter this medication. Take your medication on a regular basis. Never take it more frequently than prescribed.

Consult your pediatrician about the usage of this medication in young patients. There might be a need for extra caution.

Overdosage: Contact an emergency department or poison control center right away if you believe you may have taken too much of this medication.

References:

1.      Al-Salama ZT, Syed YY, Scott LJ. Lenvatinib: a review in hepatocellular carcinoma. Drugs. 2019 Apr 1;79:665-74.

2.      Hao Z, Wang P. Lenvatinib in management of solid tumors. The oncologist. 2020 Feb 1;25(2):e302-10.

3.      Tahara M, Kiyota N, Yamazaki T, Chayahara N, Nakano K, Inagaki L, Toda K, Enokida T, Minami H, Imamura Y, Sasaki T. Lenvatinib for anaplastic thyroid cancer. Frontiers in oncology. 2017 Mar 1;7:25.

Disclaimer:

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Marketer details

Name: Natco Pharma Ltd

Address: Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India

Country of origin: India