Genexol PM Injection contains Paclitaxel, a chemotherapy drug that belongs to the class of taxanes. It is frequently used to treat a variety of cancers, such as Kaposi's sarcoma, lung cancer, ovarian cancer, and breast cancer. By disrupting the regular function of microtubules during cell division, paclitaxel kills cancer cells that divide quickly.

Brand Name: Genexol PM

Composition: Paclitaxel 100mg

Mechanism of Action:

By stabilizing microtubules, paclitaxel stops them from breaking down during cell division, or mitosis. Because of this, the cancer cells are unable to divide fully, which results in cell death. It mostly affects cells that divide quickly, such as cancer cells.

Uses:

• Breast Cancer
• Ovarian Cancer
• Non-Small Cell Lung Cancer
• Kaposi’s Sarcoma

Dosage and Administration:

Intravenous infusion is the method. The type of cancer being treated, the patient's body surface area (BSA), and the chemotherapy regimen all affect the usual dosage of Paclitaxel.

Side Effects:

·       Nausea

·       Vomiting

·       Diarrhea

·       Rash

·       Headache

·       Weakness

·       Fever

·       Difficulty breathing

·       Allergic reactions

·       Mouth sores

·       Constipation

Safety Advise:

Kidney  

Dose adjustments are required in patients with renal impairment. Kindly speak with your healthcare provider.

Liver  

Liver function tests should be monitored during prolonged treatment, especially in patients with liver disease, as paclitaxel can cause elevated liver enzymes. Kindly speak with your healthcare provider.

Pregnancy  

Use Genexol PM during pregnancy only if clearly needed and under medical supervision, as its safety during pregnancy is not fully established.  Kindly speak with your healthcare provider.

Breast Feeding  

Caution is advised during breastfeeding since the drug can pass into breast milk. Kindly speak with your healthcare provider.

Alcohol  

The safety of using Genexol PM 100mg Injection with alcohol is unknown. Kindly speak with your healthcare provider.

Storage:

Store at temperature not exceeding 25 °C. Protect from Sunlight. 

How to use this medication?

This medication is administered intravenously. A medical expert with specialized training administers it in a hospital or clinic.

Consult your pediatrician about this medication's use in kids. Extra caution could be required.

References:

1.      Markman M, Mekhail TM. Paclitaxel in cancer therapy. Expert opinion on pharmacotherapy. 2002 Jun 1;3(6):755-66.

2.      Perez EA. Paclitaxel in breast cancer. The oncologist. 1998 Dec 1;3(6):373-89.

3.   Alves RC, Fernandes RP, Eloy JO, Salgado HR, Chorilli M. Characteristics, properties and analytical methods of paclitaxel: a review. Critical reviews in analytical chemistry. 2018 Mar 4;48(2):110-8.

4.     Priyadarshini K, Keerthi AU. Paclitaxel against cancer: a short review. Med chem. 2012 Nov;2(7):139-41.

5.      Yardley DA. nab-Paclitaxel mechanisms of action and delivery. Journal of Controlled Release. 2013 Sep 28;170(3):365-72.

Disclaimer:

The main goal of Apothecare Specialities Pvt.Ltd is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Specialities, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: Lupin Ltd

Address: Unit no 1, GR.FL., BLDG No A3, Shiv Shanti Industrial and logistics Park, Ghar No 2884, Mumbai Nashik Highway, Sonale - Bhiwandi, Thane District 421302

Country of origin: India